'Shroom Science: Safe and Effective?

Fifty years after its introduction to science, psilocybin returns to mainstream clinical research.

Written byGlenn McGee
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

In the August issue of Psychopharmacology, Johns Hopkins researchers published a study in which some subjects were given psilocybin and then asked to relate their experiences. Francisco Moreno of the University of Arizona published in the November issue of the Journal of Clinical Psychiatry his patients' reports that psilocybin helped them with migraine headaches. Harbor-UCLA Medical Center psychiatrist Charles Grob told the Chronicle of Higher Education that he is giving the compound to patients dying of cancer to see whether it eases pain by relieving anxiety.

The study of so-called magic mushrooms isn't new; it could be argued that it is celebrating its 50th anniversary this year. It began, as best anyone can tell, when Wall Street banker R. Gordon Wasson documented his trip to a healer in Oaxaca, Mexico, whose brew, he claimed, enabled him to see the reality of ideas and concepts. His 1957 essay in Life magazine ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies