Articles by Duke university neurology and neurobiology professor Allen Roses and Dennis Selkoe, a professor of neurology at Harvard University, in the September 1994 issue of the Journal of Neuropathology and Experimental Neurology thoroughly explore the amyloid and apoE hypotheses:

A.D. Roses, "Apolipoprotein E affects the rate of Alzheimer's disease expression: beta-amyloid burden is a secondary consequence dependent on apoE genotype and duration of disease," 53:429-37; D.J. Selkoe, "Alzheimer's disease: A central role for amyloid," 53:438-47.

The Alzheimer's Association (more formally known as the Alzheimer's Disease and Related Disorders Association) supports research on AD and serves as a clearinghouse for AD information. The association can be reached at P.O. Box 5675, Chicago, Ill. 60680; (800) 272-3900. Fax: (312) 335- 1110. It has a World Wide Web page at

The Alliance for Aging Research is a nonprofit advocacy organization that works to increase the priority of scientific and medical...

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