Active Motif's Chariot reagent enables rapid protein transduction The delivery of biomolecules into cells has typically been achieved through the use of chemicals, electroporation, or viral vectors. Each of these techniques has its drawbacks: for example, calcium phosphate- mediated transfections suffer from low reproducibility, electroporation-based transfections can be cytotoxic, and viral vector-based transfections pose safety concerns and can be time-consuming. In addition, these techniques
 Active Motif's Chariot reagent enables rapid protein transduction |
To help solve these problems, Active Motif of Carlsbad, Calif., has introduced the Chariot transfection reagent, which is capable of introducing molecules such as peptides, antibodies, and small and large proteins into mammalian cells. The reagent forms noncovalent complexes with the proteins, peptides, or antibodies to be delivered, generating a cage around the macromolecule that protects it ...
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