Spectrometry

J.L. Holmes, "The neutralization of organic cations," Mass Spectrometry Reviews, 8, 513-39, November 1989. John L. Holmes (University of Ottawa, Canada): "When writing this review, I was concerned that it not be just another catalog of results. It was intended to show the great promise that fast ion beam neutralization has for the generation of hitherto unknown small molecules and free radicals--but not without clearly emphasizing the pitfalls that can arise from the over-optimistic or incauti

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

J.L. Holmes, "The neutralization of organic cations," Mass Spectrometry Reviews, 8, 513-39, November 1989.

John L. Holmes (University of Ottawa, Canada): "When writing this review, I was concerned that it not be just another catalog of results. It was intended to show the great promise that fast ion beam neutralization has for the generation of hitherto unknown small molecules and free radicals--but not without clearly emphasizing the pitfalls that can arise from the over-optimistic or incautious treatment of experimental results. Perhaps this more critical approach increases citability. A significant number of laboratories are constructing mass spectrometers with these experiments in mind. The field will certainly be competitive; after all, a new molecular species can be discovered only once. I consider that the extraordinary versatility of the mass spectrometer as a tool for exciting new physicochemical research will continue to be exploited for many years to come."

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH