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Each issue, The Scientist publishes a list of top-rated papers from a specific subject area, as well as a short review of one or more of the listed papers. We also publish a selection of comments on interesting recent papers from the Faculty of 1000's output. For more information visit

Since the early 1980s, physicians have relied on the immunosuppressive drug cyclosporine (CsA) as a way to prevent allograft rejection in organ transplant patients. The problem with CsA, however, is that it also promotes tumor growth. Indeed, cancer kills many transplant patients. "It's a very bad situation to be in," says Edward...

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