Structured Water Is Changing Models

Courtesy of Martin ChaplinWater molecules cluster to form hydrogen-bonded bicyclo-octamers (H2O)8 (top left) that can link together into larger structures (top right). Ideally they form 280-member icosahedral clusters, (H2O)280, (below), shown looking down the two-fold, three-fold, and five-fold axes of symmetry. Only the oxygen atoms of the constituent water molecules are shown (except at top left).Researchers are beginning to glimpse water's secret social life. Evidence is mounting that water

Written byBennett Daviss
| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

Courtesy of Martin Chaplin

Water molecules cluster to form hydrogen-bonded bicyclo-octamers (H2O)8 (top left) that can link together into larger structures (top right). Ideally they form 280-member icosahedral clusters, (H2O)280, (below), shown looking down the two-fold, three-fold, and five-fold axes of symmetry. Only the oxygen atoms of the constituent water molecules are shown (except at top left).

Researchers are beginning to glimpse water's secret social life. Evidence is mounting that water in living systems naturally gathers into frameworks of 14, 17, 21, 196, 280, or more molecules. Some say that the clusters' apparent existence necessitates redesigning simulation models of life processes. And support is growing behind the idea that these intricate structures play key roles in operations ranging from molecular binding to turning on and off basic cell processes.

Such huge clusters certainly exist under some conditions, according to Richard Saykally, professor of chemistry at University of California, Berkeley. Saykally ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

Parse Logo

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Sino Biological Logo

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

SPT Labtech Logo

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform