Tackling severe disease with INTEGRA Biosciences electronic pipettes

Researchers at the University of Ostrava, Czech Republic, are using a 12 channel 50μl VOYAGER adjustable tip spacing pipette and ECO Rack GripTip pipette tips from INTEGRA Biosciences to study the role of protein-DNA interactions in the progression of severe diseases, such as cancers and neurodegeneration.

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These tools have enabled the team to cut pipetting times by 75 %, freeing up staff to perform other vital tasks and increasing the lab’s sample throughput.

A team within the Department of Biology uses the VOYAGER with GripTips to isolate DNA, RNA and proteins from recombinant bacteria and plants, sometimes processing more than 100 biological samples per day. The group then studies the noncanonical nucleic acids structures – such as four-stranded G-quadruplexes, left-handed Z-DNA, and cruciform DNA – and how these unusual conformations interact with proteins, providing valuable insights into the development of numerous serious conditions.

Dr Martin Bartas, a researcher in the department, explained: “We are using the 12 channel VOYAGER pipette to perform DNA and protein extractions, making it possible to carry out quick and easy transfers between 96 well qPCR or microtitration plates and 1.5 ml microtubes. We also use the pipette to rapidly fill qPCR ...

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