The Faculty of 1000 is a Web-based literature awareness tool published by BioMed Central. It provides a continuously updated insider's guide to the most important peer-reviewed papers within a range of research fields, based on the recommendations of a faculty of more than 1,400 leading researchers.

Each issue, The Scientist publishes a list of the 10 top-rated papers from a specific subject area, as well as a short review of one or more of the listed papers. We also publish a selection of comments on interesting recent papers from the Faculty of 1000's output. For more information visit

Most laboratory work is, by necessity, reductionist. A minute aspect of an organism, isolated from its contextual surroundings, is examined in excruciating detail, and the knowledge gained is pieced together with similar studies to gain a picture of the larger puzzle. A certain kinase is examined, for example, to see...

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