Each issue, The Scientist publishes a list of the 10 top-rated papers from a specific subject area, as well as a short review of one or more of the listed papers. We also publish a selection of comments on interesting recent papers from the Faculty of 1000's output. For more information visit www.facultyof1000.com.
But the biological world, especially at the sub-cellular level, does not exist merely as discrete units or even pairs, contributing nothing to the whole but the sum of their parts. Those parts interact with each other to display properties not found when taken in isolation. Witness the choreography involved as the transcriptional or translational machineries create RNA or proteins, let alone their relationships to each other.
The burgeoning field of proteomics has identified a huge number of cellular proteins. Techniques such as the two-hybrid system have indicated many pair-wise interactions among them. But that is merely "an ...
