The first 13-year-old patient

The first 13-year-old patient   By Merrill Goozner FEATURE ARTICLE Beating MalariaNicholas White and François Nosten have shown that drugs in combination with artemisinin are 90% effective at fighting the scourge of the world. So why isn't everyone using it? MERRILL GOOZNER travels to Thailand and China to watch Nosten and White at work. ARTICLE EXTRAS A military outbreak spurs researchIn September 2003, the US 26th Marine Expeditionary Unit entered Liberia for a

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By Merrill Goozner

Nicholas White and François Nosten were not the first clinicians to use artemisinin in a human trial. That honor belongs to Li Guoqian, now a senior professor at the Guangzhou University of Traditional Chinese Medicine (GUTCM).

Military necessity has always been a major driver of antimalarial therapeutic advances, and when Vietnam president Ho Chi Minh asked Chinese Community Party leader Mao Zedong for help in combating a disease that was disabling more of his soldiers than were American bombs during the Vietnam War, traditional Chinese medicine, especially qinghaosu, seemed like a good place to start. (At the time, both Vietnam and China were cut off from global supplies of chloroquine, then the drug of choice for treating malaria.)

Mao, in the midst of unleashing a Cultural Revolution that would temporarily destroy schools that taught western medicine, asked Zhou En Lai to establish a military research project on ...

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