Deshaies 02 – Open twisted Alpha/Beta structure #1, #2, #3 – 53 × 108 in. – 3–11" × 14"–28 × 36 cm – Acrylic on canvas –
Clinical proteomics is undergoing a major shift, perhaps even a revolution. What was principally a search for drug targets in the year 2000 is now more a quest for markers of disease. The hunt for a single protein has turned into a pursuit to identify patterns of polypeptides. Buzzwords such as high-throughput, personal medicine, quantitative, and multiplex are bandied about in the same breath as subproteome and bioinformatics.
"What is now emerging is sort of Proteomics II," says Leigh Anderson, CEO of the Washington, DC-based nonprofit Plasma Proteome Institute (PPI). Proteomics I was exploratory, but now there is increased focus on quantitative measurement of proteins, including patterns of quantitative changes, with an emphasis on statistics. "That's a new and important additional level ...
