Edited by: Karen Young Kreeger

FIGHTING REJECTION: William Bensinger and colleagues used recombinant cytokines to stimulate stem-cell production in transplant donors.
W.I. Bensinger, C.H. Weaver, F.R. Appelbaum, S. Rowley, T. Demirer, J. Sanders, R. Storb, C.D. Buckner, "Transplantation of allogenic peripheral blood stem cells mobilized by recombinant human granulocyte colony-stimulating factor," Blood, 85:1655-8, 1995. (Cited in nearly 100 publications as of December 1996).

Comments by William I. Bensinger, Fred Hutchinson Cancer Research Center, Seattle

Approximately 12,000 bone-marrow transplants are performed each year in the United States. Coming up with alternative sources of stem cells for transplantation as well as developing new methods to decrease the likelihood of donor cell rejection are active areas of study in transplantation biology.

This paper was among the first to describe the use of peripheral blood stem cells collected from normal donors and given to acute leukemia patients who were waiting for bone...

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