What Can We Learn From The Investigation Of Misconduct?

[Editor's note: Discussions of research misconduct are becoming more and more prevalent, in the halls of academic and research institutions as well as on the front pages of newspapers. But few in the scientific community have experienced the issue as personally as the six authors of the now infamous Cell paper, among them MIT's David Baltimore and Tufts' Thereza ImanishiKari. Since May 1986, when Margot O'Toole, a postdoc working in Imanishi-Kari's lab at MIT, first raised doubts about some of t

| 11 min read

Register for free to listen to this article
Listen with Speechify
0:00
11:00
Share

In the most recent hearing, held last month, Rep. John Dingell (DMich.), chairman of the Subcommittee on Oversight and Investigations of the House Energy and Commerce Committee, asked several people to describe how their institutions handled—or mishandled—the allegations brought by O'Toole.

What follows are excerpts from the testimonies of key figures in the dispute. The comments are not intended to prove or disprove specific allegations, nor are they meant to provide any kind of overview of this one case. Rather, they are reprinted here to provide a glimpse into how scientists at the center of such a dispute do their jobs, how they see themselves, and how they are viewed by others; as well as to illuminate some personal elements of a bitter and protracted debate.]

So what is the case against us? That there are legitimate disagreements over the results of our work? This I recognize and encourage. That ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Image of a woman with her hands across her stomach. She has a look of discomfort on her face. There is a blown up image of her stomach next to her and it has colorful butterflies and gut bacteria all swarming within the gut.
November 2025, Issue 1

Why Do We Feel Butterflies in the Stomach?

These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".

View this Issue
Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.

Long-Read RNA Sequencing Reveals a Regulatory Role for Splicing in Immunotherapy Responses

Pacific Biosciences logo
Research Roundtable: The Evolving World of Spatial Biology

Research Roundtable: The Evolving World of Spatial Biology

Conceptual cartoon image of gene editing technology

Exploring the State of the Art in Gene Editing Techniques

Bio-Rad
Conceptual image of a doctor holding a brain puzzle, representing Alzheimer's disease diagnosis.

Simplifying Early Alzheimer’s Disease Diagnosis with Blood Testing

fujirebio logo

Products

Eppendorf Logo

Research on rewiring neural circuit in fruit flies wins 2025 Eppendorf & Science Prize

Evident Logo

EVIDENT's New FLUOVIEW FV5000 Redefines the Boundaries of Confocal and Multiphoton Imaging

Evident Logo

EVIDENT Launches Sixth Annual Image of the Year Contest

10x Genomics Logo

10x Genomics Launches the Next Generation of Chromium Flex to Empower Scientists to Massively Scale Single Cell Research