Ancient DNA Sheds Light on Peopling of Americas

An analysis of centuries-old genetic material from two infants who lived near the Bering Strait suggests that people came to North America in a single wave from Asia about 25,000 years ago.

Written byBob Grant
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

The Upward Sun River site in Alaska, where researchers unearthed the infants' remains at an ancient burial groundIMAGE: BEN POTTER/UNIVERSITY OF ALASKA FAIRBANKSAncient mitochondrial genomes from infants who lived more than 11,500 years ago in Beringia—the area of North America in the vicinity of the Bering Strait—have yielded tantalizing clues about how humans moved from Asia into new territory in the Americas. Using the latest ancient DNA technology, researchers from the University of Alaska and elsewhere sequenced the genomes from human remains found at a millennia-old burial site in Alaska’s rugged interior and found that two infants—one a premature baby and the other a 6-week-old—had different mothers, even though scientists had previously assumed they were twins. The research team published the findings in PNAS on Monday (October 26).

“This is the oldest human remain we've found so far north,” study coauthor Justin Tackney of the University of Utah told Live Science.

In addition to being very old, the remains of the children turned out to be very informative. One of the babies belonged to haplogroup C1b, and the other belonged to the B2 genetic lineage. Both lineages are present in modern Native Americans, but B2 was thought to be confined to southern tribes, such as the Navajo and Anasazi. Because representatives of the B2 lineage were previously thought to be absent from northerly latitudes, some anthropologists had hypothesized that the lineage’s ancestors populated the Americas in a wave of migration that was distinct from Siberians crossing the Bering land bridge some 20,000 years ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies