Article Extra: A Genetic Diet By the Numbers

RELATED ARTICLE A Genetic Diet By the Numbers ANDREW MEEHAN and RICK CONTRERAS While a complete picture of the relationship between food, genes and complex disease has yet to be worked out, several stats point to the benefits nutrigenomic predictions might have for human health. By KATE TRAVIS ARTICLE EXTRAS Feature Article: Eat Your Way to Better DNA Related Article: NuGO: A Vision for Nutrigenomics Collaboratio

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While a complete picture of the relationship between food, genes
and complex disease has yet to be worked out, several stats point to the benefits nutrigenomic predictions might have for human health.
By KATE TRAVIS

13% Relative increase in high density lipoprotein (HDL) levels among women who ate high amounts of polyunsaturated fats and had the A allele in the promoter region of APOA1, compared with those with the more common G allele who ate similar amounts of unsaturated fat.1

23% Percentage of normal-weight mice born to mothers fed a genistein (soy isoflavone)-rich diet compared to 10% of offspring born to mothers fed phyto-estrogen-free diets. The diet produced the shift by increasing methylation at specific sites of the agouti gene, which controls both coat color and obesity in these mice.2

0.44% Percentage of Caucasians found homozygous for the 282C/Y mutation on the HFE gene, placing them at high risk of ...

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