By Hannah Waters Viral Hijackers Chris Bjornberg / Photo Researchers, Inc. (Dengue virus) The paper N.S. Heaton, G. Randall, “Dengue virus–induced autophagy regulates lipid metabolism,” Cell Host Microbe, 8:422-32, 2010. Free F1000 EvaluationThe finding Autophagy allows a cell to reuse essential molecules, eliminate bacterial invaders, or undergo programmed cell death. Nicholas Heaton and Glenn Randall at the University of Chicago discover

By Hannah Waters Truly Phenome-nal John Durham / Photo Researchers, Inc. (Antibiotic resistance in E.coli.) The paper R.J. Nichols et al., “Phenotypic landscape of a bacterial cell,” Cell, 144:143-56, 2011. Free F1000 EvaluationThe finding Advances in sequencing technology have inundated scientists with genomics data but left them with a drought of corresponding phenotypes. To address this problem, first author Robert Nichols of the University o

Bacteria and their parasitic phages evolve just as quickly in a natural soil community as they do in a test tube, but other selective pressures can influence the changes

A reevaluation of research goals in government-funded science is needed to achieve better healthcare for US citizens, according to one science policy researcher

The reanalysis of a 1958 experiment suggests that volcanic eruptions may have spawned the amino acids that contributed to the rise of life on earth

Proteins transferred to female mosquitoes during copulation affect their behavior, and provide potential targets for disease control

Measures are needed to increase the chance of success for drugs entering clinical trials

A documentary about the research of neuroscientist Robert White goes beyond his macabre head-transplant experiments to highlight his contributions to science

A genetically modified fungus that targets not mosquitoes, but the malaria parasites inside, could be a powerful tool for malaria eradication

Fish excrement found in seafloor sediment forces scientists to rethink the way they reconstruct earth's climate history

The Lab, a new interactive film from the Office of Research Integrity, is a fresh approach to research misconduct training

Human DNA sequences are found in nearly a quarter of the publically-available non-primate genomes, emphasizing the need for better quality control measures