Articles by Jack Lucentini

Technology Roundup By Jack Lucentini One of the Greater Philadelphia region's strengths is its robust science and technology research. This sampling of efforts underway at the area's institutions reveals projects ranging from basic science to cutting-edge technologies in clinical development. Many of the products under development represent part of a growing trend: a shift toward personalized medicine. Innovative Technology Greater Philadelphia Innovation -->

Lab-on-a-chip Technology Goes Nano By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix Science is moving from an age in which researchers can sequence genomes, to one in which doctors can use them in deve

Matching the Drug to the Tumor By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Rutgers-Camden Institute Neuronetics Temple University Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix BioNanomatrix When scientists at Bristol-Myers Squibb Research Institute in Princeton, NJ, recently studied whether a new drug could fight colorectal cancer, they started with a

Rutgers-Camden Institute to Focus on Integrative Biology By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Neuronetics Temple University Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix BioNanomatrix Nervous about narrowing product pipelines and costly clinical trial failures, big pharmaceutical companies

Magnets in Medicine By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Temple University Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix BioNanomatrix The technique of treating sick people with magnets might not seem ripe for Food and Drug Administration approval, given that its m

Taking the Bite out of COPD By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix BioNanomatrix In dry medical jargon, it's called an exacerbation. For the patients, it's a frightening, wrenching assault on the body that som

Testing Transporters By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University University of Pennsylvania Tengion Kimmel Cancer Center Orphagenix BioNanomatrix FDA expectations for preclinical drug testing as part of new drug applications are growing. That promises good business for Exton, Pa.-b

Drano for the Arteries By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems Tengion Kimmel Cancer Center Orphagenix BioNanomatrix If it works as hoped, it could be the next blockbuster drug: one that shrinks artery-clogging atherosclerotic plaque, the leading cause of the

Building a Better Bladder By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems University of Pennsylvania Kimmel Cancer Center Orphagenix BioNanomatrix When children with the spine malformation, spina bifida, develop a serious bladder failure, they have one, somewhat unsa

Need a Cancer Research Edge? Get on the Grid By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems University of Pennsylvania Tengion Orphagenix BioNanomatrix If cancer research is tough to begin with, coordinating it among dozens of major institutions might sound like a t

Fixing Genetic Errors By Jack Lucentini ARTICLE EXTRAS Innovative Technology Technology Roundup Greater Philadelphia Innovation --> Bristol Myers-Squibb Rutgers-Camden Institute Neuronetics Temple University Absorption Systems University of Pennsylvania Tengion Kimmel Cancer Center BioNanomatrix The paradigmatic gene therapy technique involves slipping new genes into cells on the backs of modified viruses, although other

FEATUREFuel Cells Using sugars, sludge, and the sea floor, can bacteria power the next green-energy alternative?BY JACK LUCENTINIWhen Bruce Rittmann got a $100,000 NASA grant two years ago to find ways for converting human excrement and other organic waste into electricity in spacecraft, he prepared to reach for the stars.When the space agency cut research funding, his ambitions became a bit more grounded. Usin

For more than two decades, Evan Balaban has honed his skills at manipulating embryonic tissue samples using tiny instruments of his own making. He can cut a small access window into a quail's egg, and using a scalpel no wider than a human hair, excise a few hundred thousand cells from the bird's developing central nervous system. This is only the first step of the intricate process required to place this minuscule brain into another animal's head. Some of these surgeries end in untimely

FEATUREIs This Life? BY JACK LUCENTINI Hordes of green, sub-microscopic balloons float in a watery mixture in Jack Szostak's laboratory at Harvard Medical School. They come in a variety of shapes: spheres, blimps, worms. And as Szostak examines magnified images of them, he can't help but notice a striking resemblance to bacterial ecosystems, puls

FEATUREIs This Life?Just What Is Synthetic Biology? The term "synthetic biology" appears in the title of a 1913Nature article but then disappears until the 1980s, at which pointits use seems interchangeable with recombinant DNA technology.today, the term is used to describe the wholesale engineering of geneticcircuits, entire genomes, and even organisms and has appea