Laura De Francesco
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Articles by Laura De Francesco

Taking The Measure Of The Message
Laura De Francesco | | 9 min read
Date: November 23, 1998Product Comparison Getting a measure of even a single RNA species has never been easy. Every few years, a new technique comes along--Northerns, ribonuclease protection assays, RT-PCR--that makes the task only incrementally easier. But a quantum leap in technology took place just a few years ago with the introduction of cDNA arrays, and suddenly not just one but hundreds to thousands of target nucleic acids can be analyzed simultaneously and precisely. Since then, array te

The Next New Wave In Genome Analysis
Laura De Francesco | | 7 min read
Sequencing may arguably be the premier technology of the eighties and nineties, but it has its shortcomings. For projects requiring frequent sampling or high sensitivity, conventional sequencing can be too labor intensive and expensive for laboratories outside the dedicated, high throughput sequencing centers. But a new technology is on the horizon--actually well over the horizon--that can provide genetic information simply and quickly. The discovery of a unique class of structure-specific end

Getting Down To Bases
Laura De Francesco | | 1 min read
Human Genome Program Report (1977) Prepared for the U.S. Department of Energy by the Human Genome Management Information System, Oak Ridge National Laboratories, Oak Ridge, Tenn. DNA Sequence Analysis Software Features
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