The composition and sequence of 3 billion bases of DNA serve as a major determinant of our individual physiology.

M.B. Kastan, Q. Zhan, W.S. El-Diery, F. Carrier, T. Jacks, W.V. Walsh, B.S. Plunkett, B. Vogelstein, A.J. Fornace, Jr., "A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia," Cell, 71:587-97, 1992. (Total citations through October 1994: 246) This paper is one of a number of publications from the laboratory of Michael Kastan at the Johns Hopkins Oncology Center in Baltimo

M.B. Kastan, Q. Zhan, W.S. El-Diery, F. Carrier, T. Jacks, W.V. Walsh, B.S. Plunkett, B. Vogelstein, A.J. Fornace, Jr., "A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia," Cell, 71:587-97, 1992. (Total citations through October 1994: 246) This paper is one of a number of publications from the laboratory of Michael Kastan at the Johns Hopkins Oncology Center in Baltimo