Boulder, Colo.-based Proligo, under license from Danish biotech firm Exiqon, is now marketing a novel class of nucleic acid analogs called locked nucleic acids (LNA™). Sporting increased thermal stability, higher affinity for native nucleic acids, and enhanced resistance to nuclease activity, LNA outperforms DNA in several common applications. Structurally similar to RNA, LNA monomers are bicyclic compounds that bear a methylene linker that connects the nucleotide sugar ring's 2'-oxygen

Proteomics may be the hot buzzword in biology, but proteomics researchers still lack the integrated, "off-the-shelf" tools that have come to characterize genomic research. Now, however, San Jose, Calif.-based Thermo Finnigan offers these scientists an all-in-one package with its recently released ProteomeX™ Workstation, a complete proteomics system. The ProteomeX Workstation is a multidimensional liquid chromatography/mass spectrometry (LC/MS) package that combines three successful Thermo

Estimating the number of cells in a culture is sometimes inexact, often time consuming, and always pure drudgery. Plus, when the volume of the culture is extremely small, the samples removed for cell counting make later measurements more frustrating since the scientist must then correct for the decreased volume. And of course, each time the researcher removes a sample, fewer and fewer cells remain for any downstream analyses. A German company seems to have found a solution. The soon-to-be-relea