Blue-light-sensing proteins unexpectedly help regulate virulence in at least one species of infectious bacteria, and the mechanism might prove common among other microbes, according to a study published this week in Science."There's a whole universe of bacterial photobiology to be uncovered," John Kennis at Vrije University in Amsterdam, who did not participate in this study, told The Scientist. Kennis cowrote a commentary published with the new findings.About a decade ago, researchers found that certain plant photoreceptors contain protein modules called light, oxygen, or voltage (LOV) domains, sequences roughly 110 amino acids long that absorb blue light. Since then, these domains have been identified in nearly 100 bacterial species. But because many of them are not photosynthetic and had no known or expected response to light, the function of LOV domains was unknown.Roberto Bogomolni at University of California, Santa Cruz, and his colleagues investigated LOV domains in Brucella...
abortusphosphorylatesbacteriaBrucellaBrucellaBrucella
BrucellaBrucellamelitensisBrucellaThe ScientistBrucellaEmmanuel LiscumThe ScientistArchaeaSean CrossonBrucellaThe ScientistBrucellamail@the-scientist.comSciencehttp://www.sciencemag.org http://www.few.vu.nl/~johnSciencehttp://www.sciencemag.orgSciencehttp://www.the-scientist.com/pubmed/9405347 http://www.the-scientist.com/pubmed/17571886http://www.chemistry.ucsc.edu/faculty/bogomolni.htmlThe Scientisthttp://www.the-scientist.com/article/display/13894The Scientisthttp://www.the-scientist.com/article/display/36660/ http://www.biosci.missouri.edu/liscum/LiscumLabPage.html
http://crescentus.bsd.uchicago.edu
The Scientisthttp://www.the-scientist.com/article/display/14868
BrucellaBrucellamelitensisBrucellaThe ScientistBrucellaEmmanuel LiscumThe ScientistArchaeaSean CrossonBrucellaThe ScientistBrucellamail@the-scientist.comSciencehttp://www.sciencemag.org http://www.few.vu.nl/~johnSciencehttp://www.sciencemag.orgSciencehttp://www.the-scientist.com/pubmed/9405347 http://www.the-scientist.com/pubmed/17571886http://www.chemistry.ucsc.edu/faculty/bogomolni.htmlThe Scientisthttp://www.the-scientist.com/article/display/13894The Scientisthttp://www.the-scientist.com/article/display/36660/ http://www.biosci.missouri.edu/liscum/LiscumLabPage.html
http://crescentus.bsd.uchicago.edu
The Scientisthttp://www.the-scientist.com/article/display/14868
Interested in reading more?
Become a Member of
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!