Balancing Business and Science at ImClone

Artwork: Elena Lokshina, www.artblues.com John Mendelsohn had reached the pinnacle of his scientific career when he was called before US congressional investigators this autumn to answer questions about his role in ImClone Systems, the Manhattan technology company whose CEO, Sam Waksal, later pleaded guilty to fraud and conspiracy charges. The president of the University of Texas MD Anderson Cancer Center, Mendelsohn had led the once-ailing research institution through what The Houston Chronic

| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

John Mendelsohn had reached the pinnacle of his scientific career when he was called before US congressional investigators this autumn to answer questions about his role in ImClone Systems, the Manhattan technology company whose CEO, Sam Waksal, later pleaded guilty to fraud and conspiracy charges. The president of the University of Texas MD Anderson Cancer Center, Mendelsohn had led the once-ailing research institution through what The Houston Chronicle described as a "turnaround;" he was recognized as the developer of C225 (now Erbitux), a mono-clonal antibody still praised as promising in anticancer research.1 He had even been considered as a candidate for the directorship of the National Institutes of Health, according to the Chronicle.

But that day, Oct. 10, members of the House Committee on Energy and Commerce skimmed over the details of Mendelsohn's public service and the decades of research that led to development of C225. Instead, they queried him ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Katherine Uraneck

    This person does not yet have a bio.

Published In

Share
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

agilent technologies logo