Canopy Biosciences Develops Spatial Proteomics Assay for COVID-19

Using High-Plex Spatial Proteomics to Examine Immune Response


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Canopy Biosciences, a Bruker Company, today announced the successful development of a new assay for examining immune response to COVID-19. The assay uses high-plex spatial proteomics and is performed on Canopy’s ZellScannerONE precise spatial phenotyping instrument. ZellScannerONE enables multiplexed spatial quantification of protein biomarkers in tissue samples, as well as in suspended cells. Relative to traditional techniques, such as flow cytometry, Canopy’s ChipCytometry is able to detect and quantify many more markers with spatial resolution and longer storage times.

The COVID-19 Immune Response Assay will be available initially as a service, performed by Canopy on researcher-supplied samples, and a reagent kit will be available at a later date. The COVID-19 Immune Response Assay allows researchers to spatially profile 18 different protein biomarkers. Data from these markers further enables the identification and quantification of 32 distinct cellular phenotypes, including major immune cell types as well as various cell states (e.g., exhaustion, ...

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