Genetic engineering has been boosted by the discovery and characterization of CRISPR-associated Cas9 RNA-guided endonuclease. This technology enables rapid genetic perturbation and manipulation, as well as genome-wide functional screening. With broad basic science and translational applications, this technology is driving innovative life science and medical research.
Horizon Discovery is a life science company that supplies research tools and services to organizations engaged in translational genomics research and the development of personalized medicines. Horizon’s core capabilities are built around our proprietary translational genomics platform, a high-precision and flexible suite of gene editing tools that include CRISPR, rAAV and ZFNs, enabling us to alter almost any endogenous gene sequence of human or mammalian cell-lines.
We offer over 20,000 catalogue cell line and in vivo products, models that accurately recapitulate the disease-causing mutations found in genetically based diseases. These ‘patients-in-a-test-tube’ are being used by customers to identify the effect of individual or compound ...
