BRUCE E. MARYANOFF
Distinguished Research Fellow
Assistant Director
Medicinal Chemistry
R.W. Johnson Pharmaceutical Research Institute
Spring House, Pa.
Carbohydrate Research
Topiramate is a derivative of the monosaccharide D-fructose that is under development for the treatment of epilepsy by the R.W. Johnson Pharmaceutical Research Institute (a subsidiary of Johnson & Johnson). This drug was discovered in my laboratory (U.S. Patent 4,513,006) and is currently in advanced clinical development. We have published on this anticonvulsant drug in the Journal of Medicinal Chemistry (30:880, 1987) and Drugs of the Future (14:342, 1989), and have presented our findings at t
Written byBruce Maryanoff
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