M. Muller, J. Briscoe, C. Laxton, D. Guschin, A. Ziemiecki, O. Silvennoinen, A.G. Harpur, G. Barblerl, B.A. Witthuhn, C. Schindler, S. Pellegrini, A.F. Wilks, J.N. Ihle, G. Stark, I.M. Kerr, "The protein tyrosine kinase JAK1 complements defects in interferon-a/b and g signal transduction," Nature, 366:129-35, 1993. (Cited in more than 150 publications through September 1995)

Z. Zhong, Z.L. Wen, J.E. Darnell, Jr., "STAT3-a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6," Science, 264:95-8, 1994. (Cited in about 100 publications through September 1995)

Comments by James E. Darnell, Jr., Rockefeller University; George R. Stark, Cleveland Clinic Foundation Research Institute; and Zhong Zhong, Columbia University College of Physicians and Surgeons

These papers are two among a host of highly cited reports on the subject of signal transduction involving two protein families-the JAKs and STATs-to emerge from the laboratories of James E....

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