Courtesy of Gary Churchill |
Since their rise to fame in the mid 1990s, microarrays have been both lauded and criticized. Enthusiasm about this technology, which many researchers say has forever fundamentally changed biology, is tempered by the recognition that the microarray, like any tool or technology, has its limits. Results are often hard to reproduce and interpret, and the data-driven approach encouraged by the technology can make microarray studies little more than what critics call "fishing expeditions."
Microarrays simultaneously can measure expression for hundreds, even thousands of genes, and...
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