Deep Wells and Dark Currents: CCD Cameras Offer Microscopists an Immediate, Distortion-free, Quantifiable Image

Date: July 20, 1998CCD Cameras, Image Processing Software For the biologist interested in cell structure-function relationships or cell and tissue dynamics, the quest has long been for a magnifying detector that is stable, quantitative, and sufficiently sensitive to eliminate phototoxicity or photobleaching and, in the limit, allow continuous observation without perturbation. If the data from one's detector can be immediately analyzed and displayed in a favorite software application, so much th

Written byRobert Klevecz
| 18 min read

Register for free to listen to this article
Listen with Speechify
0:00
18:00
Share

Date: July 20, 1998CCD Cameras, Image Processing Software For the biologist interested in cell structure-function relationships or cell and tissue dynamics, the quest has long been for a magnifying detector that is stable, quantitative, and sufficiently sensitive to eliminate phototoxicity or photobleaching and, in the limit, allow continuous observation without perturbation. If the data from one's detector can be immediately analyzed and displayed in a favorite software application, so much the better. Charge coupled device (CCD) cameras now offer the flexibility to acquire distortion-free, quantitative, high resolution images from a microscope or other instrument in an easily manipulated format. Image data can be efficiently collected, processed, and displayed in a number of ways. Rapid developments in other digital device designs such as charge injection device (CID) and complementary metal oxide surface (CMOS) promise to press the manufacturers of CCD cameras to even greater improvements and to put these technologies in ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH