Donald Fredrickson: Spending Hughs' Legacy

In 1975, the Howard Hughes Medical Institute (HHMI) was remarkable more for its namesake, the legendary, ultra-reclusive billionaire, than for its $3 million research program. But Hughes' death in 1976, and the 1985 sale of the Hughes Aircraft Co. for $5 billion, have made the Institute remark-able to the tune of $200 million in biomedical grants last year alone. That figure is expected to climb to $300 million by 1990, making the Institute the largest private medical research organization in th

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We're not a private foundation and are not subject to private foundation rules. We don't want to be a private foundation, but we need clarification of the definition of an MRO. What does it allow us to do and not to do? We also want to know if there are any outstanding penalties or tax issues unresolved.

The Institute has been growing very fast. But it soon is going to come into equilibrium, because we now know what our endowment is. We intend to spend at least 3½ percent of that, and probably more, over the next few years. So our spending will increase a little bit relative to NIH, but not a great deal more. We still have to grow though; we're not fully mature in our new incarnation.

It was a direct ambition of ours not to get too concentrated. We're interested really in supporting excellent people, but ...

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