Don't Clone Alone

Date: September 15, 1997 cDNA Library Kit Table and Species Chart Pre-made cDNA libraries and kits abound in the market to help you probe the secrets of gene regulation while minimizing the drudgery of cDNA library construction. The ability to analyze a cell's genetic read-out-to determine which of the 100,000 possible genes are actually being expressed in a cell or tissue-is to know what makes a cell what it is. This is a central issue in molecular biology. For decades, cDNA libraries-colle

Written byLaura Defrancesco
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Date: September 15, 1997 cDNA Library Kit Table and Species Chart

Pre-made cDNA libraries and kits abound in the market to help you probe the secrets of gene regulation while minimizing the drudgery of cDNA library construction.

The ability to analyze a cell's genetic read-out-to determine which of the 100,000 possible genes are actually being expressed in a cell or tissue-is to know what makes a cell what it is. This is a central issue in molecular biology. For decades, cDNA libraries-collections of DNA copies of mRNA species-have been hotly pursued as a way to get at this and questions of gene regulation. How important is this? So important that a technique for identifying rare messages was the subject of a $20 million lawsuit a few years ago (K. Young Kreeger, The Scientist, Oct 2, 1995, page 1). So important that companies have been amassing literally hundreds of cDNA libraries ...

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