Laura Defrancesco
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Articles by Laura Defrancesco

Programmed to Die
Laura Defrancesco | | 6 min read
James King-Holmes/Science Photo Library Predicting natural death is generally impossible, save for those who study Caenorhabditis elegans: They know the precise moment that 131 cells, and only those 131 cells, are programmed to die. The timing and location of cell death is identical during the development of every tiny C. elegans worm. Nobel laureates John Sulston and Robert Horvitz discovered these cellular suicides in 1976 when they mapped the fate of C. elegans' 1,090 cells. "It really di

Special Delivery
Laura Defrancesco | | 7 min read
Courtesy of Nadine Barrie Smith PATCHING THROUGH: The ultrasound patch, weighing less than 22 grams, is an array made from up to four cymbal transducers, encased in a flexible polymer. This array's dimensions are 37 x 37 x 7 mm. It can be made thinner. Proteins represent the largest class of biotech drug ap-provals, and the numbers will continue to rise as work with the human genome sequence proceeds. Figures from 2000 show that 86% of 77 approved biotech medicines are proteins, with hu

Physics Rules
Laura Defrancesco | | 1 min read
Frontlines | Physics Rules One wonders what force Dylan Thomas was pondering when he wrote: "The force that through the green fuse drives the flower/ Drives my green age." Chances are the poet wasn't considering genetics, but that shouldn't bother researchers Paul Kulesa and Scott Fraser. They've discovered that physical forces may be more important than gene expression during the development of chick somites, or embryonic segments. The prevailing view has been that molecular biology driv

Mixed support for genetics
Laura Defrancesco | | 3 min read
Largest US survey ever finds public accepts some genetic technology, wants govt control.

Researcher seeks whistleblower protection
Laura Defrancesco | | 3 min read
Marine Fisheries scientist charges US government with endangering salmon.

Mexico ocean survey shut down
Laura Defrancesco | | 2 min read
Federal magistrate issues temporary restraining order.

Whales and sounds
Laura Defrancesco | | 3 min read
Low-frequency acoustic noise implicated in Baja California whale deaths.

Biotech claims comprehensive SNP map
Laura Defrancesco | | 2 min read
Perlegen amasses 1.7 million human SNPs with high-density arrays

Journal trio embraces MIAME
Laura Defrancesco | | 3 min read
t will require researchers to comply with microarray standard

Biotech pioneer dies
Laura Defrancesco | | 2 min read
Bruce Wallace, pivotal figure in Amgen's history, dies at 54

In Style, but...Out of Reach
Laura Defrancesco | | 4 min read
Image: Erica P. Johnson Treating people who have seizure disorders is a little like playing roulette. Place a bet on a drug from column A and hope for a hit. If that drug doesn't work, try one from column B. This process can drag on for months or years, and for many people with epilepsy--between 25% and 30%--relief from seizures never comes. With 40 to 50 million people experiencing seizures worldwide, this means that huge numbers of people receive no benefit from treatment. One might think t

California endorses stem cell research
Laura Defrancesco | | 2 min read
New state law expected to lure researchers and business.

Agro-terrorism threat
Laura Defrancesco | | 2 min read
Report calls for tighter controls and more research on agricultural pathogens.

Graduate admissions crackdown
Laura Defrancesco | | 2 min read
UCLA scrutinizing foreign biomedical applicants following Chinese transcript fraud case

MIAME begets MAGE
Laura Defrancesco | | 2 min read
Improved data format debuts but universal microarray repositories still on the horizon.
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