Researchers have linkurl:retracted a highly-cited 2003 Nature Genetics paper; which identified mutations underlying some types of epilepsy after discovering some blatantly erroneous results that negate the study's main finding, they report in the September issue of the journal.
Generic family pedigree
Image: Wikimedia commons,
Armin Kübelbeck
"I think it's appalling, to be perfectly honest," said Massimo Pandolfo of the linkurl:Hôpital Erasme; of the Université Libre de Bruxelles in Belgium, who was not involved in the original publication, but cited the 2003 paper in his own work. "This goes beyond any degree of acceptable mistake." The 2003 Nature Genetics article, which has been cited 187 times, according to ISI, claimed that four common subtypes of an inherited form of epilepsy were associated with three different mutations in a single gene coding for a chloride-gated ion channel. The work involved analysis of three different families and identified an autosomal dominant pattern of...
Nature GeneticsNature Genetics

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