Evolution in Oil Droplets

For the first time, researchers have mimicked biological evolution using chemicals instead of living organisms.

Written byBob Grant
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

Examples of different oil droplet behavior observed in the experimentImage from Nature CommunicationsIt’s not exactly survival of the fittest, but researchers in Scotland have shown that oil droplets can exhibit a rudimentary form of evolution. The nonbiological system comprised more than 200 different droplet types composed of four chemicals that exhibited predictable behaviors when dropped into petri dishes full of water. The scientists analyzed the droplets’ fitness based on those behaviors, and found that they could direct the evolution of more stable droplets.

Glasgow University chemist Lee Cronin, who led the work, told WIRED.co.uk that the experiment is an important demonstration of the principles that may have spurred nonliving components to give rise to living things. “Right now, evolution only applies to complex cells with many terabytes of information but the open question is where did the information come from?” he said. “We have shown that it is possible to evolve very simple chemistries with little information.” (See “RNA World 2.0,” The Scientist, March 2014.) Cronin and his colleagues published the work yesterday (December 8) in Nature Communications.

The researchers used a robot based on a simple 3-D printing platform that created oil droplets at random from combinations of four different chemicals—1-octanol, diethyl phthalate, 1-pentanol, and either octanoic ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies