Gene Names

Regarding your article on gene names (P. Smaglik, The Scientist, 12[7]:1, March 30, 1998), you make a couple of major errors in the yeast example. This does go to show the difficulty of different systems of nomenclature, but also, the information in your box on page 6 should be corrected. It's not just yeast, but fission yeast, S. pombe. Accepted nomenclature is not wee-1 (as you write), but wee1+. It does not make an abnormally small protein, but rather, the mutant causes the yeast to divide

Written bySusan Forsburg
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

Regarding your article on gene names (P. Smaglik, The Scientist, 12[7]:1, March 30, 1998), you make a couple of major errors in the yeast example. This does go to show the difficulty of different systems of nomenclature, but also, the information in your box on page 6 should be corrected. It's not just yeast, but fission yeast, S. pombe. Accepted nomenclature is not wee-1 (as you write), but wee1+. It does not make an abnormally small protein, but rather, the mutant causes the yeast to divide at an abnormally small size--it's the cells that are small.

The wee1 protein has homologues in all eukaryotes and is an important kinase that regulates cell division. The correct nomenclature, if not its derivation, is readily found in the literature. If you ever require further information on fission yeast S. pombe< nomenclature, please visit our Web page at http://flosun.salk.edu/~forsburg/plasmids.html#nomenclature.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Image of a man in a laboratory looking frustrated with his failed experiment.
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies