Genome Digest

What researchers are learning as they sequence, map, and decode species’ genomes

Written byJyoti Madhusoodanan
| 5 min read

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FLICKR, KEVIN DOOLEY

Species: Domestic cat (Felis catus)
Genome size: 3.1 billion base pairs

Domestic cats can develop diseases like leukemia and feline immunodeficiency virus . To better understand these diseases, an international team of researchers sequenced and annotated the genomes of three domestic cats. The results, published this month (August 5) in GigaScience, include a new feline genome browser, Genome Annotation Resource Fields (GARfield), which encompasses methylation patterns in cat blood cells and more than 21,000 annotated genomic features.

A team led by investigators at Nova Southeastern University in Florida sequenced and analyzed the genomes of three cats using three different methods. While the feline genome was previously published, Nova Southeastern researcher Stephen O’Brien and his colleagues noted that their work helps to close gaps in the ...

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