Massive Animal Sequencing Effort Releases First Set of Genomes
Jef Akst | Sep 13, 2018
The Vertebrate Genomes Project has released data on 14 vertebrate species, but the goal is to sequence all 66,000.
Thousands of BRCA1 Genetic Variants Functionally Characterized
Sukanya Charuchandra | Sep 13, 2018
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
As Bees Specialize, So Does Their DNA Packaging
Shawna Williams | Sep 11, 2018
A study of chemical tags on histone proteins hints at how the same genome can yield very different animals.
Anti-CRISPR Proteins Found that Block Cas12a Nuclease
Ashley Yeager | Sep 6, 2018
Using bioinformatics, two teams of scientists identified inhibitory proteins for Cas9’s relative.
RNA Detection Tool Debate Flares Up at ACS Meeting
Katarina Zimmer | Sep 5, 2018
Researchers have flagged several issues with so-called SmartFlares over the years, and it’s still unclear why they don’t appear to work under certain circumstances.
Early Results of First In Vivo Gene-Editing Trial Encouraging
Kerry Grens | Sep 5, 2018
Two patients who received Sangamo’s zinc finger–based treatment for Hunter syndrome have lower biomarkers of the condition, but no signs of new enzyme production.
Image of the Day: Ocean Wonder
Sukanya Charuchandra | Sep 4, 2018
Molecules similar to those produced by sea anemones are neuroprotective in a mouse cell model of Alzheimer’s disease.
US Companies Launch CRISPR Clinical Trial
Catherine Offord | Sep 3, 2018
The Germany-based study will test an ex vivo genome-editing therapy for the inherited blood disorder β-thalassemia.
CRISPR Treatment for Duchenne Muscular Dystrophy Helps Dogs
Catherine Offord | Aug 31, 2018
Researchers boosted levels of the dystrophin protein to nearly normal levels in a canine model of the disease.