Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.
Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.

genetics & genomics
Prenatal Sequencing for Some Autism Genes May Soon Be Available
Prenatal Sequencing for Some Autism Genes May Soon Be Available
Jessica Wright | Apr 22, 2019
Two studies, taken together, imply that sequencing can identify a genetic cause for ultrasound abnormalities in roughly 10 percent of cases.
Mice Gene-Edited While Still in the Womb
Mice Gene-Edited While Still in the Womb
Chia-Yi Hou | Apr 19, 2019
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Image of the Day: Pretty Jellies
Image of the Day: Pretty Jellies
Chia-Yi Hou | Apr 19, 2019
The genomes of jellyfish are compared with those of other Cnidarian species that don’t have a free-swimming stage.
Genetic Risk Score Developed for Obesity
Genetic Risk Score Developed for Obesity
Kerry Grens | Apr 18, 2019
The tool weighs millions of variants to determine how susceptible a person is to becoming obese.
Gene Therapy Effective for Severe Combined Immunodeficiency
Gene Therapy Effective for Severe Combined Immunodeficiency
Shawna Williams | Apr 17, 2019
Researchers report they’ve found a way to restore immune function in infants with one form of “bubble boy disease.”
Astronaut Study Shows Some Lasting Changes from Time in Space
Astronaut Study Shows Some Lasting Changes from Time in Space
Kerry Grens | Apr 11, 2019
Scott Kelly’s physiology, gene activity, and mental performance changed after time aboard the International Space Station, but mostly returned to normal once back on Earth.
Monkeys Genetically Edited to Mimic Human Brain Development
Monkeys Genetically Edited to Mimic Human Brain Development
Chia-Yi Hou | Apr 10, 2019
Rhesus monkeys engineered to express a human gene reportedly show delayed brain development and better short-term memory. Fellow scientists are raising ethical red flags.
Sydney Brenner, mRNA Discoverer, Dies
Sydney Brenner, mRNA Discoverer, Dies
Kerry Grens | Apr 5, 2019
One of the foremost molecular biologists of the 20th century, the Nobel laureate established C. elegans as a model organism, mapping its genes and development.
Q&A: Epigenetic Therapies for Breast Cancer
Q&A: Epigenetic Therapies for Breast Cancer
Katarina Zimmer | Apr 4, 2019
Breast cancer researcher and oncologist Nancy Davidson discusses what we’ve learned from the first wave of epigenetic trials for breast cancer, and what challenges lie ahead before such therapies reach the clinic.