HHS Secretary Sullivan To Determine If NIH Gene Patent Quest Is Over

The decision on whether the National Institutes of Health should continue its quest for patents on partial human cDNA sequences now rests with Health and Human Services secretary Louis Sullivan. In September, NIH director Bernadine Healy revealed that the agency had received an initial rejection from the United States Patent and Trademark Office (PTO) for the approximately 2,700 partial gene sequences generated by former NIH researcher Craig Venter and others. Then, on October 5, an HHS spok

Written byScott Veggeberg
| 6 min read

Register for free to listen to this article
Listen with Speechify
0:00
6:00
Share

Then, on October 5, an HHS spokesperson said that Secretary Sullivan would be briefed on the situation by the end of that week, and that he would issue his decision "shortly thereafter" on whether NIH should shelve the patents or respond to objections raised in the PTO rejection and continue with the process.

The partial DNA sequences covered in the patents, also known as expressed tag sequences (ESTs), are thought to be useful tools to locate complete gene sequences. But NIH, which saw the possibility that publication of these partial sequences could preclude a later patent on the entire sequence, submitted patent applications. Many in the research community saw the applications as unnecessary and obstructive to progress in the Human Genome Project (Scott Veggeberg, The Scientist, April 27, 1992, page 1).

More than five months into the search for a new Human Genome Project (HGP) director, the hunt continues, with ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Image of a man in a laboratory looking frustrated with his failed experiment.
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies