How to tango with DMSO – A smart way to evaporate tough solvents

When it comes to organic synthesis, drug discovery, or natural products/polymer chemistry, one of the trickiest but most ubiquitous steps in the workflow is evaporation. For many years, chemists have struggled with the task of rapidly and efficiently evaporating solvents that have high boiling points – think DMF or DMSO. The standard rotary evaporator in the lab is not ideal for getting rid of these solvents; it is painstakingly slow in such cases, must be closely monitored, and can easily bump.

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When it comes to organic synthesis, drug discovery, or natural products/polymer chemistry, one of the trickiest but most ubiquitous steps in the workflow is evaporation. For many years, chemists have struggled with the task of rapidly and efficiently evaporating solvents that have high boiling points – think DMF or DMSO. The standard rotary evaporator in the lab is not ideal for getting rid of these solvents; it is painstakingly slow in such cases, must be closely monitored, and can easily bump.

One cannot escape the use of DMF or DMSO in organic synthesis or NMR analysis, so most of the time a researcher would resign to using the lab’s rotary evaporator – while also pulling out their hair at the inefficiency and bottleneck it creates in the workflow.

To spare chemists everywhere of this hassle (and help save some of their hair), BioChromato developed a solution – a smarter way ...

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