Illuminating Images: The World of Phosphor Screen and Fluorescence Imaging Systems

Date: February 16, 1998 Chart 1 Chart 2 nyone tired of mixing darkroom chemicals should read this article. The modern generation of instruments for viewing both radioactively and fluorescently labeled samples can save you countless hours of time and provide quantitation only dreamed of by researchers in the past. The products to consider are phosphor screen and fluorescent imagers. These handy devices offer numerous advantages over film autoradiography: Sensitivity: estimates of sensitivity

Written byLaura Defrancesco

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Date: February 16, 1998

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nyone tired of mixing darkroom chemicals should read this article. The modern generation of instruments for viewing both radioactively and fluorescently labeled samples can save you countless hours of time and provide quantitation only dreamed of by researchers in the past. The products to consider are phosphor screen and fluorescent imagers. These handy devices offer numerous advantages over film autoradiography:

For the most part, these advantages apply to imaging and analyzing fluorescence as well, for which there was little beyond color photography (except very sophisticated and expensive image processing instruments) for documenting and analyzing this kind of data. There are currently at least three broad categories of instruments: those that image only radioactivity (Fuji Medical's BAS Series, Molecular Dynamics' PhosphorImager SI, and Packard Instrument's CycloneTM and InstantImager"), those that measure only fluorescence (Molecular Dynamics' FluorImager 595), and those that do both, or ...

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