K.C. Garcia, M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, I.A. Wilson, "An alpha-ß T cell receptor structure at 2.5Å and its orientation in the TCR-MHC complex," Science, 274:209-19, 1996. (Cited in more than 240 papers since publication)
Comments by Ian A. Wilson, professor of molecular biology at The Scripps Research Institute in La Jolla, Calif.
D.N. Garboczi, P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, D.C. Wiley, "Structure of the complex between human T-cell receptor, viral peptide, and HLA-A2," Nature , 384:134-41, 1996. (Cited in more than 210 papers since publication)
Comments by David N. Garboczi, intramural investigator at the National Institute of Allergy and Infectious Diseases in Bethesda, Md., and Partho Ghosh, assistant professor of chemistry and biochemistry at the University of California, San Diego.
The Scripps team's representation of the TCR-MHC complex is shown above. The pMHC is underneath with the peptide (P1-P8) ...
