(The Scientist, Vol:4, #22, pg. 20, November 12, 1990) (Copyright, The Scientist, Inc.)
-------- R.C. Desrosiers, M.S. Wyand, T. Kodama, D.J. Ringler, et al., "Vaccine protection against simian immunodeficiency virus infection," Proceedings of the National Academy of Sciences, 86, 6353-57, August 1989.
Ronald Desrosiers (New England Regional Primate Research Center, Harvard Medical School, Southborough, Mass.): "A vaccine would likely be of greatest public health benefit in stemming the increasing spread of AIDS. However, making a vaccine to protect against the AIDS virus, HIV, is probably going to be a very difficult task. The difficulties stem largely from the properties of the virus itself and the nature of the persistent infection. HIV, like other members of the lentiretrovirus subgroup, produces a long-term, persistent infection and chronic disease course in spite of an apparently strong host immune response to the infecting virus. Infected individuals may remain clinically well for years, maintaining high ...
