Joining Forces

Bioengineers combine mussel and bacterial proteins to make waterproof glue.

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An adhesive composed of bacterial curli fibers (red) and mussel foot proteins (blue and green) sticks to the silica tip of an atomic force microscope.YAN LIANG

Marine mussels cling tightly to rocks, where they withstand the impact of crashing waves thanks to impressively sticky proteins in their feet. Bioengineers at MIT fused two different mussel foot proteins with curli fibers, which are produced by E. coli bacteria in biofilms, to create a new underwater adhesive. The glue, which the researchers presented this week (September 21) in Nature Nanotechnology, is the strongest known protein-based, underwater adhesive.

The scientists genetically engineered E. coli to churn out the hybrid proteins. When purified, the proteins self-assembled into chain-like fibers. The team used atomic force microscopy to probe the fibers, testing their ability to adhere to silica, gold, and polystyrene surfaces. They found that the resulting engineered glue was significantly stickier than any of its individual ...

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