Two of the implanted valves lasted a full year as the animals matured into adult sheep, demonstrating that it might be possible to treat children with valve replacements that grow along with them.

This year yielded stunning images of transparent human organs, apex predators, and the world’s response to the ongoing pandemic.

Molly Shoichet and Bridget Wagner discuss strategies for using phenotypic screening to identify novel agents against diseases such as cancer and diabetes.

Scientists rely on synthetic biology and cell-free expression systems for developing novel approaches to combat the pandemic.

A newly engineered synthetic blood vessel offers a novel platform for developing drugs that treat high blood pressure.

There’s a new cell-based cancer immunotherapy on the block.

An experimental tissue engineering treatment that addresses damage at both the inner core and outer ring of sheep intervertebral discs improves spinal structure and function.

Researchers and clinicians make small muscle grafts into the arms of amputees to amplify the signals from their peripheral nerves, which then direct the movement of a robotic hand.

Three-dimensional polymer matrices offer researchers a new representation of the extracellular matrix that can be used to study the growth of cancer cells.

Scientists carve the shapes from piles of frog cells, like a sculptor building a statue.

A 3-D printed rabbit is made from a blueprint stored in DNA, which itself is stored in a printed rabbit.

Physicists, geneticists, computer scientists, and biologists are working together to gain a full appreciation of the intricacies of organismal growth and form.

Technology is enabling increasingly lifelike models of organs to help doctors practice operations.

A new portable instrument could help to lure useful bugs in from the wild.

Genes inserted into the yeast genome produce the compounds CBD and THC in the microbes.

The pea-size machine uses body fluids as fuel to propel itself through the digestive tract.

With genetic tweaks, researchers can coax corn and other cereals to take in more iron, but sometimes the plants rebel.

The agritech industry is editing plant genomes to feed a growing population, expand the produce aisle, and make tastier, more convenient food products.

Researchers have outfitted brewer’s yeast with light-harvesting semiconductors to boost chemical productivity.