This year yielded stunning images of transparent human organs, apex predators, and the world’s response to the ongoing pandemic.

Molly Shoichet and Bridget Wagner discuss strategies for using phenotypic screening to identify novel agents against diseases such as cancer and diabetes.

Scientists rely on synthetic biology and cell-free expression systems for developing novel approaches to combat the pandemic.

A newly engineered synthetic blood vessel offers a novel platform for developing drugs that treat high blood pressure.

There’s a new cell-based cancer immunotherapy on the block.

An experimental tissue engineering treatment that addresses damage at both the inner core and outer ring of sheep intervertebral discs improves spinal structure and function.

Researchers and clinicians make small muscle grafts into the arms of amputees to amplify the signals from their peripheral nerves, which then direct the movement of a robotic hand.

Three-dimensional polymer matrices offer researchers a new representation of the extracellular matrix that can be used to study the growth of cancer cells.

Scientists carve the shapes from piles of frog cells, like a sculptor building a statue.