Lateral Thinking

For this article, Steve Bunk interviewed Claire M. Fraser, president, the Institute for Genomic Research, Rockville, Md. Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. K.E. Nelson, R.A. Clayton, S.R. Gill, M.L. Gwinn, R.J. Dodson, D.H. Haft, E.K. Hickey, J.D. Peterson, W.C. Nelson, K.A. Ketchum, L. McDonald, T.R. Utterback, J.A. Malek, K.D. Linher, M.M. Garrett, A.M. Stewart, M.D. Cotton

Written bySteve Bunk
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

TIGR president Claire M. Fraser, senior author of this paper, says that eventually a set of rules might be devised concerning lateral gene transfer, perhaps involving engulfment of one cell by another. For now, though, the picture is becoming more complicated as evidence accumulates. "It's much easier to imagine all this going on when you're talking about single-cell organisms," she comments.

The paper announced the sequencing of the bacterium Thermotoga maritima, a hyperthermophile that was originally isolated from geothermally heated marine sediment. Comparing its genome to all 16 other then-sequenced microorganisms, the researchers found that almost one-quarter of its genes were most similar to those of archaeal species. Moreover, 81 of the 451 Archaea-like genes were clustered in regions that often contained a gene order conserved between Archaea and T. maritima, suggesting that large regions of DNA were acquired through lateral transfer. But the most compelling evidence came from phylogenetic ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

Published In

Share
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH