MAIL

Mendel upended? I was interested in this story1 when the 2005 paper came out, suggesting that Arabidopsis mutants could revert to wild type, and I started doing some experiments to test Susan Lolle and Robert Pruitt's ideas. My early data seemed to support the notion that reversion was happening (although it was not consistent with RNA-mediated reversion). When Steve Jacobsen's paper came out I decid

Written byThe Scientist
| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

I was interested in this story1 when the 2005 paper came out, suggesting that Arabidopsis mutants could revert to wild type, and I started doing some experiments to test Susan Lolle and Robert Pruitt's ideas. My early data seemed to support the notion that reversion was happening (although it was not consistent with RNA-mediated reversion).

When Steve Jacobsen's paper came out I decided to grow hothead in isolation. I chose two isolated environments, and out of about 1,500 plants I didn't see any revertants. So I stopped working on this project because, like most of the community, I believed Jacobsen's results. But, I was never totally comfortable with this because of my early data. I'm glad Lolle is working on finding out how much outcrossing contributes to reversion and am anxious to see her results.

Emily Updegraff
University of Chicago
Chicago, IL
epupdegr@uchicago.edu

This is a nice in-depth update on ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH