For the most part, endothelin has been the focus of investigations by molecular biologists and biochemists--not clinicians. During the past year, however, Burnett and his team have added a new dimension to endothelin research; a dimension that has received considerable attention from the rest of the research community.
John Burnett's team has been on a winning streak in the past few months as the Mayo group of clinicians had two more endothelin studies accepted for publication: one appeared in the August issue of the American Journal of Physiology (P.G. Cavaro, et al., "Endothelin in experimental congestive heart failure in the anesthetized dog," 259:F312-17, August 1990), and one is to be published in the January 1991 issue of Circulation. The team also presented a third paper at the Central Society for Clinical Research conference in Chicago two weeks ago. Using a dog model to mimic human heart failure, the team has ...
