Paul Kefalides
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Articles by Paul Kefalides

Apathy, Outrage Accompany Leak Of Unofficial Report On Gallo Case
Paul Kefalides | | 10+ min read
Document questions conduct of HIV researcher and NIH,but many grass-roots scientistssay they are tiring of the case. ROBERT GALLO: The NIH researcher calls the subcommittee report "bizarre" and a personal attack on him. Grass-roots scientists have had a muted response to the underground release of an investigative report on alleged misconduct by National Institutes of Health HIV researcher Robert C. Gallo prepared by a former majority congressman's staff. Notwithstanding the relative lack of

Johnson Grants Let Scientists Take Risks
Paul Kefalides | | 5 min read
In 1989, when Harvard University geneticist Rachael Neve sought funding to test her controversial hypothesis on Alzheimer's disease, her requests fell on deaf ears. "I had been writing a proposal to [the National Institutes of Health] for a year and a half, and it kept getting rejected," recalls Neve, who challenged the conventional wisdom in neuroscience with data indicating that the toxic protein responsible for Alzheimer's was some 60 amino acids longer than previously thought. "I applied to

Proliferation Of Research Parks Conceals Uneven Success Pattern
Paul Kefalides | | 9 min read
Research parks usually exist on university land that is leased for a long term. The parks host industrial scientists and other workers, as well as university researchers from natural science and occasionally social science disciplines. The main attraction to private industry is the university, particularly access to its faculty and educated work force, libraries, and special instrumentation facilities. For university scientists, the draw is the added vigor of aligning their work with a company'

Hot Team: Modern Science Lab Has An Old World Accent
Paul Kefalides | | 7 min read
The University of Chicago laboratories of the prolific Richard J. Miller, a 41-year-old British neuropharmacology professor, is a study in cultural contrasts. Animated discussions of neurotransmitters are punctuated with dry British humor; and while classical music permeates Miller's office, rock 'n' roll is king in the labs, where he has attracted many scientists from his native country. In Miller's labs, which are part of the department of pharmacology and physiological sciences, playful, ba

Oncologist Leads Research Group To Genetics' Cutting Edge
Paul Kefalides | | 7 min read
At the University of Wisconsin's McArdle Laboratory for Cancer Research in Madison, oncology professor Waclaw Szybalski and his team are helping to define the leading edge of genetic engineering. The methods they have developed could have a tremendous impact on the much-discussed Human Genome Project, and it is therefore not surprising that Szybalski and his team of three senior researchers and three graduate students spend long hours in the lab. Indeed, even when they are not working, the rese

Mayo Team Of MD's Advances Field Of Vascular Biology
Paul Kefalides | | 7 min read
In the medical research arena, the M.D.'s have generally stuck with their stethoscopes, leaving the work of discovering to the Ph.D.'s. But at the Mayo Clinic in Rochester, Minn., a research group led by cardiologist John C. Burnett, Jr., and composed entirely of medical doctors is charging ahead to decipher the physiologic role of endothelin, a peptide that causes narrowing of the blood vessels. For the most part, endothelin has been the focus of investigations by molecular biologists and bio
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