Oncologist Leads Research Group To Genetics' Cutting Edge

At the University of Wisconsin's McArdle Laboratory for Cancer Research in Madison, oncology professor Waclaw Szybalski and his team are helping to define the leading edge of genetic engineering. The methods they have developed could have a tremendous impact on the much-discussed Human Genome Project, and it is therefore not surprising that Szybalski and his team of three senior researchers and three graduate students spend long hours in the lab. Indeed, even when they are not working, the rese

| 7 min read

Register for free to listen to this article
Listen with Speechify
0:00
7:00
Share

The success of the team at the 50-year-old McArdle Laboratory may be partly due to this friendly relationship among its members. But it is the atmosphere within the laboratory that seems to spur the researchers on. The team operates without formal structure but with tremendous individual familiarity. Says senior researcher Noaman Hasan, "We are independent in our work, but there is a lot of interaction when there are problems." Adds Szybalski, "I am of the mind that one plus one equals more than two."

University of Wisconsin oncologist Waclaw Szybalski and two of his graduate students, Michael Koob and Eric Grimes, borrowed from Greek mythology to describe Achilles' heel cleavage, the bioengineering that allows them to cut long pieces of DNA in one predetermined spot. According to the myth, Achilles was rendered virtually immortal by his mother, Thetis, when she dipped him in the River Styx. She held him by ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Meet the Author

  • Paul Kefalides

    This person does not yet have a bio.

Published In

Share
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Stem Cell Strategies for Skin Repair

Stem Cell Strategies for Skin Repair

iStock: Ifongdesign

The Advent of Automated and AI-Driven Benchwork

sampled
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo

Products

dispensette-s-group

BRAND® Dispensette® S Bottle Top Dispensers for Precise and Safe Reagent Dispensing

Sapio Sciences

Sapio Sciences Makes AI-Native Drug Discovery Seamless with NVIDIA BioNeMo

DeNovix Logo

New DeNovix Helium Nano Volume Spectrophotometer

Olink Logo

Olink® Reveal: Accessible NGS-based proteomics for every lab

Olink logo