The editors and readers of the journal Molecular Carcinogenesis could argue that the shift to mechanistic toxicology proposed in Marcia Clemmitt's recent article in The Scientist (Feb. 17, 1992, page 1) has already occurred. For the past five years, Molecular Carcinogenesis has been reporting the growth of, and changes in, all fields of carcinogenesis, including toxicology.

The need for a journal that emphasized the causative mechanisms of cancer at the molecular level became apparent in 1987, when the burgeoning field of molecular biology made it possible to examine carcinogenesis at a more intimate level. In conjunction with the University of Texas M.D. Anderson Cancer Center and Wiley-Liss Inc. of New York, we started Molecular Carcinogenesis as a peer-reviewed forum for work on the molecular mechanisms of carcinogenesis.

Advances in molecular biology have enabled us to move from what University of Maryland pathology professor Ellen Silbergeld referred to in the article...

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