Date: August 31, 1998Table 1: Molecular Modeling Software, Table 2: Structure & Modeling Information and Table 3: Visualization & Image Resources The term "molecular modeling" usually conjures up two images: three-dimensional (3-D) depictions of small molecular structures (for example, benzene) and biological macromolecular structures (for example, proteins, DNA, and RNA). Some of the earliest and perhaps most renowned 3-D representations of a biological macromolecule were the wire-frame and paper models of deoxyribonucleic acid developed by James Watson and Francis Crick, who used this physical modeling technique to decipher the arrangement of deoxyribonucleotides in the DNA "double helix" (J.D. Watson, "The Double Helix," Antheneum, 1968). Within the next decade, computational tools had made their way into molecular structure analysis. Although crude by today's standards, these tools contributed to the structural analyses of cytochrome c and myoglobin. For an interesting historical perspective, read Cyrus Levinthal's "Molecular Model Building by Computer" (Scientific American, ...
Molecular Modeling - Seeing the Whole Picture with Modeling Software Packages
Date: August 31, 1998Table 1: Molecular Modeling Software, Table 2: Structure & Modeling Information and Table 3: Visualization & Image Resources The term "molecular modeling" usually conjures up two images: three-dimensional (3-D) depictions of small molecular structures (for example, benzene) and biological macromolecular structures (for example, proteins, DNA, and RNA). Some of the earliest and perhaps most renowned 3-D representations of a biological macromolecule were the wire-fram
Written byChristopher Smith
| 12 min read
Register for free to listen to this article
Listen with Speechify
0:00
12:00
Share
Interested in reading more?
Become a Member of
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
